Preparative And Process Chromatography Market Size, Share & Trends Analysis Report By Product (Process Chromatography, Preparative Chromatography), By End-use (Food, Nutraceutical), By Type, And Segment Forecasts, 2023 - 2032

The global preparative and process chromatography market was valued at USD $9.60 billion in 2022 and it is predicted to surpass around USD $22.89 billion by 2032 with a CAGR of 9.08% from 2023 to 2032.

Key Pointers

• The product segment is divided into process/analytical chromatography and preparative chromatography. Process chromatography held the largest share of 59.03% in 2022.
• The liquid chromatography segment accounted for the largest share of 27.3% in 2022.
• The pharmaceutical segment accounted for the largest share of 41.12% in 2022.
• North America dominated the global market with the highest share of 31.43% of the overall revenue, followed by Europe.
• Asia Pacific region is expected to register the fastest growth rate over the forecast period.

Report Scope of The Preparative And Process Chromatography Market:

The growth of this market is driven by the rising demand and approval of monoclonal antibodies in the pharmaceutical and biotechnology sectors. In addition, the market is driven by the expanding biopharmaceutical industry, the demand for advanced purification techniques, and the need for more efficient and cost-effective processes. Technological advancements and the development of innovative chromatography products are expected to boost market growth. For instance, in October 2021, CEM launched the prodigy preparative high-performance liquid chromatography (HPLC) system.

The system offers an elevated temperature capability, resulting in enhanced resolution and separation capabilities. The COVID-19 pandemic had a favorable impact on the market owing to the high demand for COVID-19 vaccines and treatment medications. Similarly, the pharmaceutical and biotechnology industries are likely to experience significant growth in the future driven by the emerging production and demand for preparative and process chromatography. The separation process and preparative chromatography can be employed in the analysis of materials for the manufacturing of the coronavirus vaccine.

A chromatography system is a scientific technique used for isolating specific components from sample mixtures. Analytical and preparative chromatography systems are widely employed in qualitative and quantitative methods to analyze biotechnological, pharmaceutical, and other components. The market for chromatography systems is experiencing growth due to various factors, including the increasing demand for insulin and omega-3 fatty acids, rising concerns related to food quality & safety, and the growing geriatric population. Moreover, ongoing research paradigms focusing on the separation and analysis of monoclonal antibodies using mild reverse-phase chromatography are expected to drive research in this market.

Companies are actively involved in developing flexible and robust platforms for the continuous production of monoclonal antibody products, leading to an increased demand for quality control measures. The market is experiencing growth due to the high demand for preparative techniques, technological advancements in chromatography, and the large-scale integration of liquid chromatographic techniques in downstream processing. Affinity chromatography has emerged as a pivotal tool to purify proteins as it is based on highly specific interactions occurring between the protein of interest and an immobilized ligand.

The Downstream Process (DSP) or the product purification process is one of the costliest aspects of modern bioprocess protocols, particularly with respect to proteins. Hence, in these cases, chromatography serves as a crucial tool at all stages of DSP, from early initial capture to the final polishing or finishing steps. Preparative techniques have gained wide acceptance for the purification of APIs and the key drivers associated with this expanding acceptance include improved throughput, cost-effectiveness, and purity. These techniques offer the users sufficient material volume at the desired quality for the initiation of clinical and preclinical trials. This, in turn, opens alternative routes for commercialization with minimum time invested in product development.

Global Preparative And Process Chromatography Market Report Segmentation:

Product

• Process Chromatography

• • System

• • • Multi Use Batch Chromatography Systems
    • Single-Use Batch Chromatography Systems
    • Continuous Chromatography Systems

• • Consumables

• • • Reagents
    • Resins

• • • • Affinity Resins
      • Ion-exchange Resins
      • Size-exclusion Resins
      • Hydrophobic Interaction Resins
      • Reversed Phase Resins
      • Mixed mode/Multi-mode Resins

• • • Columns

• • • • Prepacked Columns
      • Automated Columns
      • Manual Columns

• • Service

• Preparative Chromatography

• • System

• • • Semi-Preparative Chromatography Systems
    • Other Chromatography Systems

• • Consumables

• • • Reagents
    • Resins

• • • • Affinity Resins
      • Affinity Resins
      • Ion-exchange Resins
      • Size-exclusion Resins
      • Hydrophobic Interaction Resins
      • Reversed Phase Resins
      • Mixed-mode/Multi-mode Resins

• • Columns

• • • Prepacked Columns
    • Empty Columns

• • Service

Type

• Liquid Chromatography

• • HPLC
  • Flash/Column Chromatography
  • Ion-exchange chromatography
  • Size-exclusion chromatography
  • Affinity chromatography

• Gas Chromatography
• Thin Layer Chromatography
• Paper Chromatography
• Gel-permeation (Molecular Sieve) Chromatography

Hydrophobic Interaction Chromatography

End-use

• Pharmaceutical
• Biotechnology
• Food
• Nutraceutical
• Others